Table 3. Differentially expressed functional categories indicative of M. tb respiratory and metabolic state in type II AEC.
| Functional Group | Description/Association | # of Genes | Hypergeometric Probability (P value) | Range of Fold Change |
|---|---|---|---|---|
| NADH DH1 (14) a | Aerobic respiration | 7 (up) | 2.66E-05 (2.90E-05) b | +2.3 to +5.4 |
| Cytochrome c Reductase (3) | Aerobic respiration | 2 (up) | 0.01807 (0.01895) | +2.5 to +3.6 |
| Cytochrome c Oxidase (4) | Aerobic respiration | 1 (up) | 0.1888 (0.2076) | +3.2 |
| NADH DH2 (2) | Alternative Electron Transfer | NDE | N/A | N/A |
| Nitrate Reductase & Transport (5) | Non-aerobic respiration | 3 (down) | 0.000367 (0.0003705) | -2.1 to -6.6 |
a Number within parentheses indicates total number of genes in the M. tb genome within this functional group
b Bold number within parentheses indicates statistical significance, i.e., P value ≤ 0.05