Table 2. GO:C5 MS5-upregulated mRNA pathways.
Gene Set Description | P | # Up | # Down |
---|---|---|---|
Cellular Component | (none met criterion P<0.01) | ||
Molecular Function | |||
3',5'-cAMP Phosphodiesterase Activity | 0.003 | 11 | 2 |
Cyclic Nucleotide Phosphodiesterase Activity | 0.004 | 12 | 2 |
N-methyltransferase Activity | 0.001 | 8 | 5 |
Oxidoreductase Activity | 0.008 | 18 | 12 |
Phosphatase Inhibitor Activity | 0.001 | 10 | 1 |
Phosphatase Regulator Activity | 0.009 | 19 | 6 |
Serotonin Receptor Activity | 0.001 | 7 | 3 |
SH2 Domain Binding | 0.005 | 11 | 4 |
Sodium Channel Activity | 0.008 | 10 | 5 |
Transcription Elongation Regulator Activity | 0.009 | 7 | 3 |
Biological Process | |||
B Cell Activation | 0.008 | 11 | 8 |
Behavior | 0.003 | 76 | 57 |
Calcium-mediated Signaling | 0.003 | 11 | 4 |
cAMP-Mediated Signaling | 0.004 | 40 | 23 |
Cell Activation | 0.007 | 38 | 30 |
Central Nervous System Development | 0.0002 | 64 | 53 |
Chromosome Organization and Biogenesis | 0.003 | 7 | 3 |
Endothelial Cell Proliferation | 0.0001 | 7 | 3 |
G Protein Receptor Pathway | 0.0004 | 175 | 142 |
Hormone Secretion | 0.002 | 12 | 4 |
Leukocyte Differentiation | 0.010 | 21 | 14 |
Lymphocyte Activation | 0.010 | 13 | 7 |
Multicellular Organismal Process | 0.0002 | 76 | 62 |
Muscle Contraction | 0.0001 | 13 | 5 |
Myeloid Cell Differentiation | 0.005 | 11 | 6 |
Negative Regulation of Catalytic Activity | 0.003 | 37 | 28 |
Neurological System Process | 0.004 | 201 | 152 |
Positive Regulation of Cell Adhesion | 0.001 | 8 | 3 |
Regulation of Homeostasis | 0.003 | 8 | 4 |
Response to Extracellular Stimulus | 0.007 | 18 | 14 |
Second Messenger-mediated Signaling | 0.001 | 85 | 61 |
Gene sets (GO:C5) with mRNAs exhibiting upregulated expression due to neonatal morphine (MS5) exposure. Alphabetical order.