Table 5. Biocarta MS5-responsive Gene sets.
| Pathway (Biocarta) | P | # Up | # Down |
|---|---|---|---|
| UP | |||
| β-Arrestin Src | 0.0001 | 13 | 1 |
| CDK5 | 0.0022 | 8 | 2 |
| CSK | 0.0027 | 14 | 5 |
| ERK | 0.0001 | 17 | 10 |
| GLEEVEC | 0.0065 | 15 | 7 |
| HER2 | 0.0018 | 16 | 4 |
| IGF1R | 0.0029 | 13 | 8 |
| MAL | 0.0015 | 12 | 5 |
| NO2-dep IL12 | 0.0044 | 14 | 3 |
| DOWN | |||
| ACE2 | 0.0023 | 2 | 9 |
| AHSP | 0.0015 | 2 | 8 |
| ARF | 0.0015 | 4 | 12 |
| CARM1 | 0.0027 | 7 | 5 |
| MTA3 | 0.0005 | 4 | 13 |
| PTC1 | 0.0002 | 4 | 7 |
| TGFB | 0.0046 | 11 | 8 |
| VITCB | 0.0081 | 3 | 8 |
| MIXED | |||
| AMI | 0.0023 | 3 | 17 |
| DEATH | 0.0015 | 9 | 21 |
| NF-κB | 0.0057 | 4 | 19 |
| RB | 0.0003 | 1 | 11 |
| SODD | 0.0002 | 1 | 9 |
Gene sets (Biocarta) with mRNAs affected by neonatal morphine (MS5). Alphabetical order.