Figure 1.

Influence of atorvastatin, simvastatin and ezetimibe on NOS3 mRNA expression in HUVEC. Columns and error bars represents mean and SEM and were compared with the vehicle control stimulated with TNFα [(0 tnf); dotted line)] by one-way ANOVA followed by Tukey post-test. HUVEC were treated for 24 h and stimulated with human TNFα (10 ng/mL) 6 h before RNA extraction. Data were obtained from 4-6 independent experiments and mRNA expression was calculated using the comparative Ct method using the HMBS as endogenous reference. (*), p < 0.05.