Fig. 3.
Morphologic hallmarks of apoptosis are evident in Crizotinib treated SUDHL-1 cells: SUDHL-1 cells were incubated with 1 μM of Crizotinib for 72 hrs and morphologically examined after cytospin preparation. (A) Untreated control cells. (B) Treated cells showing extensive cell nuclear shrinkage, fragmentation of chromatin and vacuolization (see inset) consistent with apoptosis (1000×).