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. Author manuscript; available in PMC: 2015 Apr 6.

Published in final edited form as: Circ Heart Fail. 2013 Dec 30;7(2):261–270. doi: 10.1161/CIRCHEARTFAILURE.113.000895

Kaplan-Meier survival curves grouped by diuretic efficiency and diuretic dose in the Penn cohort (Panel A) and ESCAPE cohort (Panel B) Loop diuretic dose and diuretic efficiency were dichotomized into high and low by the median value in each cohort. “Low loop dose” was also defined as a loop diuretic dose above or below the median value which was 280 mg (120–600) in the Penn cohort and 240 mg in 24 hours (120–400) in the ESCAPE cohort.

Kaplan-Meier survival curves grouped by diuretic efficiency and diuretic dose in the Penn cohort (Panel A) and ESCAPE cohort (Panel B) Loop diuretic dose and diuretic efficiency were dichotomized into high and low by the median value in each cohort. “Low loop dose” was also defined as a loop diuretic dose above or below the median value which was 280 mg (120–600) in the Penn cohort and 240 mg in 24 hours (120–400) in the ESCAPE cohort.