Table 3. MTR_asym and MTR as a function of saturation power in healthy volunteers (N = 6).

Saturation transfer parameters derived from white matter (WM) and gray matter (GM) regions with standard errors across N=6 healthy volunteers. (†) represent statistically significant differences between WM and GM.

	0.5 μT	1.5 μT	3 μT	6 μT
MTRasym (2ppm) [%]
WM	−0.72 ± 0.02 †	0.65 ± 0.07	2.23 ± 0.08	2.20 ± 0.07
GM	−0.45 ± 0.04 †	0.96 ± 0.12	2.34 ± 0.11	2.41 ± 0.08
MTRasym (3.5ppm) [%]
WM	−1.36 ± 0.04 ††	−1.26 ± 0.06 †	0.81 ± 0.04	2.14 ± 0.05
GM	−0.86 ± 0.05 ††	−0.35 ± 0.14 †	1.12 ± 0.10	2.31 ± 0.12
MTRasym (20ppm) [%]
WM	−0.24 ± 0.01	−1.08 ± 0.02 ††	−0.87 ± 0.04 ††	−0.41 ± 0.02
GM	−0.08 ± 0.05	−0.62 ± 0.06 ††	−0.52 ± 0.05 ††	−0.15 ± 0.06
MTR(+20ppm) [%]
WM	0.48 ± 0.01	8.05 ± 0.22 ††	13.20 ± 0.25 ††	26.49 ± 0.39 ††
GM	0.36 ± 0.04	4.92 ± 0.16 ††	8.41 ± 0.25 ††	19.41 ± 0.29 ††
MTR(−20ppm) [%]
WM	0.72 ± 0.01 †	9.13 ± 0.22 ††	14.07 ± 0.28 ††	26.91 ± 0.39 ††
GM	0.44 ± 0.04 †	5.55 ± 0.17 ††	8.93 ± 0.27 ††	19.56 ± 0.33 ††

^†P < 0.04

^††P < 0.008