Table 5. MTR_asym and MTR as a function of saturation power in glioma patients (N = 8).

Saturation transfer parameters derived from tumor regions (ASL hyperintensity and Gd enhancement) and from contralateral normal appearing brain with standard errors across N=8 glioma patients. (†) represent statistically significant differences between tumor and contralateral regions. No statistically significant differences were found between the two tumor regions.

	0.5 μT	1.5 μT	3 μT	6 μT
MTRasym (2ppm) [%]
ASL hyperintensity	−0.23 ± 0.06 ††	1.17 ± 0.13 †	2.18 ± 0.15	2.54 ± 0.14
Gd enhancement	−0.28 ± 0.05 ††	1.02 ± 0.11	2.02 ± 0.10	2.45 ± 0.14
Contralateral	−0.51 ±0.02	0.65 ± 0.06	2.13 ± 0.07	2.36 ± 0.10
MTRasym (3.5ppm) [%]
ASL hyperintensity	−0.48 ± 0.05 †††	0.31 ± 0.16 †††	1.24 ± 0.10 ††	2.33 ± 0.12
Gd enhancement	−0.49 ± 0.07 †††	0.17 ± 0.21 †††	1.04 ± 0.07††	2.18 ± 0.16
Contralateral	−0.98 ± 0.06	−0.89 ± 0.10	0.73 ± 0.08	2.13 ± 0.04
MTRasym (20ppm) [%]
ASL hyperintensity	−0.07 ± 0.02 †	−0.30 ± 0.05 †††	−0.33 ± 0.05 †††	−0.07 ± 0.06†
Gd enhancement	−0.05 ± 0.03†	−0.34 ± 0.08 †††	−0.41 ± 0.06 †††	−0.10 ± 0.08†
Contralateral	−0.15 ± 0.02	−0.78 ± 0.06	−0.68 ± 0.03	−0.35 ± 0.05
MTR(+20ppm) [%]
ASL hyperintensity	0.14 ± 0.03†	3.75 ± 0.58†	6.09 ± 0.69 ††	14.10 ± 1.02 †††
Gd enhancement	0.15 ± 0.05 †	3.81± 0.72†	5.93 ± 0.94 ††	13.84 ± 1.39 †††
Contralateral	0.30 ± 0.02	6.09 ± 0.26	10.24 ± 0.32	21.38 ± 0.51
MTR(−20ppm) [%]
ASL hyperintensity	0.20 ± 0.04 †††	4.05 ± 0.62†	6.42 ± 0.70 ††	14.17 ± 1.031 †††
Gd enhancement	0.20 ± 0.04 †††	4.15 ± 0.73†	6.34 ± 0.96 ††	13.94 ± 1.37 †††
Contralateral	0.45 ± 0.02	6.87 ± 0.28	10.92 ± 0.33	21.73 ± 0.50

^†Regions statistically different from contralateral P < 0.02

^††Regions statistically different from contralateral P < 0.001

^†††Regions statistically different from contralateral P < 0.0001