Table 2.

Factors associated with (preventable) ADEs

		All patients				Patients > 65 years
Factors		OR (95% CI) ADE	P value	OR (95% CI) pADE	P value	OR (95% CI) ADE	P value	OR (95% CI) pADE	P value
Age (years)	≤ 52 years	1		1		–		–
	53–64 years	1.62 (1.26, 2.08)	0.000	0.84 (0.49, 1.45)	0.540	–		–
	65–76 years	1.75 (1.40, 2.19)	0.000	1.45 (0.94, 2.24)	0.093	1		1
	≥ 77 years	2.12 (1.70, 2.65)	0.000	2.55 (1.69, 3.84)	0.000	1.21 (1.02, 1.43)	0.027	1.76 (1.30, 2.38)	0.000
Gender	Male	1		1		1		1
	Female	1.09(0.95, 1.25)	0.242	1.07 (0.82, 1.38)	0.616	0.99 (0.83, 1.17)	0.875	1.02 (0.76, 1.38)	0.874
Clinical service	Surgical	1		1		1		1
	Non-surgical	1.04 (0.91, 1.20)	0.534	1.30 (1.01, 1.69)	0.045	0.92 (0.77, 1.08)	0.306	1.05 (0.78, 1.41)	0.751
Urgency of admission (n = 5295)	Planned	1		1		1		1
	Acute	0.94 (0.82, 1.08)	0.367	1.22 (0.94, 1.58)	0.137	0.97 (0.82, 1.14)	0.687	1.16 (0.86, 1.56)	0.330
Polypharmacy * (n = 3812)	No	1		1		1		1
	Yes	1.21 (1.03, 1.44)	0.024	1.85 (1.34, 2.56)	0.000	1.10 (0.90, 1.35)	0.335	1.58 (1.10, 2.27)	0.013

Crude odds ratios (OR) are presented based on logistic regression analysis. ADEs, adverse drug events; pADEs, preventable adverse drug events.

^*Data from three studies [10,11,17].