Table 5.
ADE classification
| Type of ADE | Frequency (% of all ADEs n = 1304)˜ | Preventable (% of all pADEs n = 265) | Severe (% of all severe ADEs)*† | Associated with high risk drugs (%) |
|---|---|---|---|---|
| Diarrhoea or constipation | 345 (26) | 16 (6) | 24 (7) | 188 (35) |
| Abnormal liver function tests | 161 (12) | 5 (2) | 79 (52) | 101 (19) |
| Central nervous system event | 184 (14) | 48 (18) | 133 (83) | 96 (18) |
| Skin and/or allergic reaction | 156 (12) | 42 (16) | 7 (5) | 62 (11) |
| Impaired haemostasis | 23 (2) | 13 (5) | 13 (65) | 19 (4) |
| Renal function disorder | 38 (3) | 16 (6) | 20 (69) | 18 (3) |
| Cardiovascular event | 58 (4) | 28 (11) | 16 (43) | 13 (2) |
| Other | 85 (7) | 28 (11) | 20 (47) | 12 (2) |
| Haemorrhage | 65 (5) | 19 (7) | 50 (79) | 11 (2) |
| Electrolyte imbalance | 32 (2) | 22 (8) | 3 (23) | 8 (1) |
| Respiratory insufficiency | 12 (1) | 5 (2) | 9 (90) | 7 (1) |
| Nausea and/or vomiting | 131 (10) | 13 (5) | 10 (9) | 6 (1) |
| Thromboembolic event | 3 (0) | 3 (1) | 0 | 0 |
| Hypoglycaemia | 11 (1) | 7 (3) | 8 (80) | 0 |