Table 2.

NEURON model predictions for the effect of preserved axon length (x) on fitted Boltzmann parameters under various regimes

Regime	AIS (μm)	Internode (μm)	Ra (Ω cm)	Rm (kΩ cm2)	D (pS μm−2)	V (pS μm−2)
Simulation regimes. is the M specific conductance in the nodes, hillock and AIS ( = 0 elsewhere). It was adjusted to obtain
Gmax ≈ 8 nS for x ≥ 100 μm, similar to the observed values (compare Fig. 7B with Table1). VM and kM were similarly adjusted
(compare Fig. 7A and C with Table1, respectively): VM(D) = −51 mV, VM(V) = −46 mV, kM = 4 or 5 mV
I	20	100	150	25	120	117
II	20	25	150	25	109	110
III	100	25	150	25	90	97
IV	100	25	75	50	60	65
V	100	25	37.5	100	42	41.5

Regime	D ΔGmax (nS)	V ΔGmax (nS)	D ΔVhalf (mV)	V ΔVhalf (mV)	D Δk (mV)	V Δk (mV)
Predicted effect of preserved axon length (x). Change in fitted Boltzmann parameters from x = 20 to x = 100 μm.
Data were derived from Fig. 7A–C.
I	0.68	0.65	0.51	0.51	0.37	0.36
II	1.14	1.09	0.92	0.90	0.69	0.67
III	2.25	2.00	1.81	1.54	2.34	2.12
IV	4.11	3.90	3.00	3.07	2.65	2.46
V	5.15	4.00	3.47	3.77	2.36	2.39

Boltzmann parameters G_max, V_half and k were estimated from fits of eqn 2 to the model predictions for G(V) but with G₀ = f(V) = 0 (e.g. Fig. 7D). D, dorsal CA1; V, ventral CA1.