Table 2.

Clinical trials investigating the effect of antioxidants on CVD

Treatment	Patients No.	Result	Ref.
β-Carotene	39 876	No benefit	Hennekens et al. (1996)
Vitamin A+ β-carotene	14 641	No benefit	Omenn et al. (1996)
Vitamin E	22 071	No benefit	Lee et al. (2005)
Vitamin C + E + β-carotene	73 135	No benefit	Cook et al. (2007)
Vitamin C + E	8171	No benefit	Sesso et al. (2008)
Vitamin B6 + B12 + folic acid	6837	No benefit	Ebbing et al. (2010)
Multivitamin	14 641	No benefit	Sesso et al. (2012)
Vitamin C	Meta-analysis	Adverse effects	Chen et al. (2013)