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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Nucl Med Biol. 2014 Dec 20;42(5):488–493. doi: 10.1016/j.nucmedbio.2014.12.008

Table 1.

Binding affinity of iodo-ASEM. values are mean ± SEM (n=3)

nAChR subtype Ki, nM α7-nAChR Binding selectivity
α7 (rat) 0.5 ± 0.2
α3β4 (human) 45 ± 8 α7/α3β4 = 90
α4β2 (human) 1707 ± 373 α7/α4β2 = 3,414