Table 2.
Regional brain distribution of [125I]iodo-ASEM in CD-1 mice. Data: mean %ID/g tissue ± SD (n=3)
| Region | 5 min | 20 min | 60 min | 120 min | 180 min | 240 min | 360 min |
|---|---|---|---|---|---|---|---|
| Cerebellum | 4.25±0.42 | 5.20±2.08 | 2.56±0.35 | 1.41±0.08 | 0.76±0.15 | 0.38±0.05 | 0.21±0.04 |
| Hippocampus | 3.63±0.40 | 5.09±0.86 | 4.40±0.12 | 3.40±2.03 | 2.66±0.58 | 1.70±0.28 | 0.97±0.12 |
| Cortex | 4.78±0.47 | 6.25±0.28 | 6.50±0.57 | 4.29±0.42 | 2.74±0.55 | 1.40±0.06 | 0.72±0.12 |
| Superior & inferior Colliculi | 4.09±0.71 | 5.50±0.51 | 5.14±0.20 | 4.37±0.57 | 3.16±0.75 | 1.50±0.28 | 0.87±0.08 |
| Rest of brain | 3.89±0.42 | 4.90±0.24 | 4.60±0.18 | 3.24±0.26 | 2.09±0.40 | 1.051±0.10 | 0.57±0.05 |