Figure 3. MXD3 knock-down reduces preB ALL cell proliferation.
MXD3 knock-down in Reh (▲, shMXD3) resulted in decreased cell numbers when compared to a negative control shRNA (■, shCTRL) or non-transduced cells (●, NT). Simultaneous knock-down and expression of MXD3 restored cell numbers to basal levels (x, shMXD3+rescue). Experiments were performed in triplicate; error bars represent standard deviation (*p < 0.001, 2-way ANOVA with Bonferroni post-test).
