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. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: Neuropharmacology. 2015 Jan 31;93:146–154. doi: 10.1016/j.neuropharm.2015.01.013

Figure 2.

Figure 2

Representative METH intake and body weight during self-administration, and hyperthermia during the binge exposure to METH. Rats were allowed to self-administer METH (0.12 mg/infusion; normalized to mg/kg) for 7 d (8 h/d; Panel A). Body weight was recorded daily (Panel B). Sixteen h after the last self-administration session rats received a binge exposure to METH (7.5 mg/kg) or saline (1 mL/kg) and hyperthermia was recorded 30 min and 90 minutes following each injection (as indicated by the arrows; Panel C). *p<0.05 METH/METH compared to Saline/METH