Table 4.
Comparison of the catalytic efficiency of MCO1 orthologs with four substrates.
| Hydroquinone | Dopamine | Ferrous iron | Ascorbate | |
|---|---|---|---|---|
| DmMCO1 isoforms | ||||
| DmMCO1T | 4 | 3 | 156 | 8,806 |
| DmMCO1T[R454A] | 6 | 2 | 359 | 5,516 |
| AgMCO1 isoforms | ||||
| AgMCO1T | 3 | 0.4 | 30 | 7,559 |
| AgMCO1T[R542S] | 2 | 0.2 | 16 | 2,785 |
| TcMCO1 isoforms | ||||
| TcMCO1Ts | 29 | 0.4 | 7 | 39,766 |
| TcMCO1Tl | 24 | 0.3 | 5 | 25,357 |
| MsMCO1 isoforms | ||||
| MsMCO1Ts | 0.8 | 0.8 | 16 | 4,838 |
| MsMCO1Tl | 0.8 | 0.9 | 6 | 5,244 |
| Insect laccases | ||||
| AgMCO3 | 302 | 171 | 5 | 233 |
| TcLac2A | 213 | 51 | 3 | very low |
| Fungal laccase | ||||
| TvLac-α | 51,661 | 12,597 | 2,407 | 135 |
| Ferroxidase | ||||
| Fet3pa | 5 | NDb | 8,000 | ND |
| Ascorbate oxidase | ||||
| Curcubita AO | ND | ND | ND | 127,558 |
Note: catalytic efficiency is reported as min-1 mM-1
a
Data are from Stoj et al., 2006
b
ND = not determined