Fig. 2.

Mean BREOS Perfusion by smoking status (estimated mean ± standard error from a group model with the 4 substance using groups; covariate were 3-year monthly drinking average and body mass index). LD group mean shown only for comparison.

BREOS Brain Reward/Executive Oversight System

sALC Smoking individuals dependent on alcohol only

nsALC Non-smoking individuals dependent on alcohol only

sPSU Smoking alcohol dependent individuals with comorbid stimulant dependence

sPSU Non-smoking alcohol dependent individuals with comorbid stimulant dependence

LD Light/non-drinking controls