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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Alzheimers Dement. 2014 Oct 7;11(9):1069–1079. doi: 10.1016/j.jalz.2014.07.156

Table 3. Correlations of Change.

Correlations between change in AB40 and change in each other indicated variable as estimated by multivariate outcome mixed-effect models. We estimated the lower and upper bounds of the 95% confidence intervals by 1,000 simulations. Correlations that are significantly different form zero are indicated in bold.

Variable MCI AD
Corr. (95% CI) Corr. (95% CI)
Aβ40 Aβ42 0.842 (0.779,0.912) 0.713 (0.606,0.804)
ADAS-Cog −0.038 (−0.152,0.075) −0.016 (−0.206,0.179)
ADL −0.072 (−0.181,0.044) −0.043 (−0.239,0.144)
MMSE −0.071 (−0.197,0.051) −0.015 (−0.204,0.176)
Urea nitrogen −0.024 (−0.161,0.106) -
Creatinine 0.034 (−0.094,0.159) -
Total protein 0.015 (−0.112,0.131) -
Albumin 0.010 (−0.125,0.128) -
Total Cholesterol 0.039 (−0.090,0.175) −0.001 (−0.199,0.199)
Hemoglobin −0.014 (−0.149,0.125) -
Platelets 0.170 (0.036,0.308) -

Aβ42 ADAS-Cog 0.044 (−0.062,0.162) 0.033 (−0.147,0.216)
ADL −0.100 (−0.218,0.006) −0.040 (−0.219,0.141)
MMSE −0.115 (−0.251,0.002) −0.081 (−0.278,0.114)
Urea nitrogen 0.053 (−0.077,0.186) -
Creatinine 0.032 (−0.108,0.156) -
Total protein −0.035 (−0.167,0.085) -
Albumin −0.065 (−0.194,0.071) -
Total Cholesterol −0.021 (−0.148,0.100) −0.127 (−0.303,0.050)
Hemoglobin −0.079 (−0.205,0.044) -
Platelets 0.038 (−0.095,0.161) -

log ratio of Aβ42 to Aβ40 ADAS-Cog 0.145 (0.019, 0.274) −0.089 (−0.263, 0.120)
ADL −0.178 (−0.309,−0.055) 0.185 (−0.008, 0.351)
MMSE 0.062 (−0.073, 0.205) −0.048 (−0.239, 0.143)
Urea nitrogen −0.168 (−0.305,−0.039)
Creatinine 0.009 (−0.133, 0.152)
Total protein −0.060 (−0.193, 0.074)
Albumin −0.098 (−0.228, 0.043)
Total Cholesterol −0.018 (−0.151, 0.118) 0.161 (−0.021, 0.360)
Hemoglobin −0.087 (−0.222, 0.031)
Platelets −0.085 (−0.212, 0.052)