Table 3. Correlations of Change.
Correlations between change in AB40 and change in each other indicated variable as estimated by multivariate outcome mixed-effect models. We estimated the lower and upper bounds of the 95% confidence intervals by 1,000 simulations. Correlations that are significantly different form zero are indicated in bold.
| Variable | MCI | AD | |
|---|---|---|---|
| Corr. (95% CI) | Corr. (95% CI) | ||
| Aβ40 | Aβ42 | 0.842 (0.779,0.912) | 0.713 (0.606,0.804) |
| ADAS-Cog | −0.038 (−0.152,0.075) | −0.016 (−0.206,0.179) | |
| ADL | −0.072 (−0.181,0.044) | −0.043 (−0.239,0.144) | |
| MMSE | −0.071 (−0.197,0.051) | −0.015 (−0.204,0.176) | |
| Urea nitrogen | −0.024 (−0.161,0.106) | - | |
| Creatinine | 0.034 (−0.094,0.159) | - | |
| Total protein | 0.015 (−0.112,0.131) | - | |
| Albumin | 0.010 (−0.125,0.128) | - | |
| Total Cholesterol | 0.039 (−0.090,0.175) | −0.001 (−0.199,0.199) | |
| Hemoglobin | −0.014 (−0.149,0.125) | - | |
| Platelets | 0.170 (0.036,0.308) | - | |
|
| |||
| Aβ42 | ADAS-Cog | 0.044 (−0.062,0.162) | 0.033 (−0.147,0.216) |
| ADL | −0.100 (−0.218,0.006) | −0.040 (−0.219,0.141) | |
| MMSE | −0.115 (−0.251,0.002) | −0.081 (−0.278,0.114) | |
| Urea nitrogen | 0.053 (−0.077,0.186) | - | |
| Creatinine | 0.032 (−0.108,0.156) | - | |
| Total protein | −0.035 (−0.167,0.085) | - | |
| Albumin | −0.065 (−0.194,0.071) | - | |
| Total Cholesterol | −0.021 (−0.148,0.100) | −0.127 (−0.303,0.050) | |
| Hemoglobin | −0.079 (−0.205,0.044) | - | |
| Platelets | 0.038 (−0.095,0.161) | - | |
|
| |||
| log ratio of Aβ42 to Aβ40 | ADAS-Cog | 0.145 (0.019, 0.274) | −0.089 (−0.263, 0.120) |
| ADL | −0.178 (−0.309,−0.055) | 0.185 (−0.008, 0.351) | |
| MMSE | 0.062 (−0.073, 0.205) | −0.048 (−0.239, 0.143) | |
| Urea nitrogen | −0.168 (−0.305,−0.039) | ||
| Creatinine | 0.009 (−0.133, 0.152) | ||
| Total protein | −0.060 (−0.193, 0.074) | ||
| Albumin | −0.098 (−0.228, 0.043) | ||
| Total Cholesterol | −0.018 (−0.151, 0.118) | 0.161 (−0.021, 0.360) | |
| Hemoglobin | −0.087 (−0.222, 0.031) | ||
| Platelets | −0.085 (−0.212, 0.052) | ||