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. Author manuscript; available in PMC: 2016 Apr 10.
Published in final edited form as: Exp Cell Res. 2015 Feb 13;333(1):39–48. doi: 10.1016/j.yexcr.2015.02.002

Table 2.

Essential PiT-1 amino acids and mutations that affect Pi transport.

Human PiT-1 Mouse PiT-1 Mutation
Glu70 (E70) Glu74 (E74) Glutamic acid → Lysine (E74K) [21]
Ser128 (S128) Ser132 (S132) Serine → Alanine (S132A) [22]
Ser621 (S621) Ser623 (S623) Serine → Alanine (S623A) [23]

Mutations in human PiT-1 that were described in previous studies to be essential for Pi transport are listed with the corresponding amino acid in mouse PiT-1. The mutation described that inhibited Pi transport is listed with the annotation describing the mouse PiT-1 mutation.