Figure 5.
CBD inhibits lung metastasis in different mouse model systems. Representative lung images and H&E staining photomicrographs were taken of control and CBD‐treated groups of 4T1.2 (A) and MVT‐1 (B) mouse models. The number of metastatic lung nodules was counted for 4T1.2 (C) and MVT‐1 (D) mouse models of control and CBD‐treated groups. Total lung weight was determined for 4T1.2 (E) and MVT‐1 (F) mouse models of control and CBD‐treated groups. RT‐PCR quantification was performed for MMP‐9 and MMP‐2 in 4T1.2 (G) and MVT‐1 (H) mouse models in control and CBD‐treated tumors 18S rRNA primers were used for loading control purpose.