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. 2014 Dec;17(12):1012–1019.

Table 1.

The mean value of different parameters in control (C), sensitized (S), sensitized pretreated with thymoquinone (S+TQ), sensitized pretreated with selective A2A antagonist (ZM241385) and selective A2B antagonist (MRS1706) (S+Anta A2A and S+Anta A2B), sensitized groups pretreated with selective A2A antagonist and thymoquinone (S+Anta A2A+TQ) and selective A2B antagonist and thymoquinone (S+Anta A2B+TQ). Statistical differences between pretreated groups vs S+TQ group: NS: non significant differences, +; P<0.05, ++; P<0.01, +++; P<0.001

The mean value of C S S+TQ S+Anta A2A S+Anta A2B S+Anta A2A+ TQ S+Anta A2B+ TQ
EC50 5.31±0.71 1.50±0.36 2.35±0.14 1.38±0.24 3.10±0.54 2.18±0.51 3.43±0.64
++ NS NS NS
OA 4.85±3.18 62.88±9.12 22.49±4.42 64.72±9.01 44.49±13.95 24.27±6.32 21.67±2.95
++ NS NS NS
Contractility 0.58±0.04 1.63±0.08 1.28±0.19 1.84±0.21 1.27±0.05 1.41±0.19 1.23±0.23
NS NS NS NS
LLF WBC 2580±180.02 9421.43±1609.1 6073.14±879.86 9896.43±288.8 5950±1035.7 7923.57±523.79 4825.0±552.59
++ Ns Ns Ns
LLF eosinophil 9.47±1.34 45.73±2.23 15.4±1.14 52.47±1.83 21±0.55 30.93±0.82 19.4±2.37
+++ +++ +++ Ns
LLF monocyte 5.33±0.53 0.86±0.32 3.20±0.24 0.73±0.25s 5.06±0.38 1.33±0.28 4.0±0.36
+++ +++ +++ Ns
LLF lymphocyte 72.467.2±3.02 42.93±2.02 63.67±3.19 33.87±1.99 70.13±1.37 61.87±1.17 66.53±2.46
+++ Ns Ns Ns
LLF neutrophil 5.60±0.73 0.53±0.19 4.93±0.54 0.80±0.24 5.87±0.50 2.40±0.47 6.06±0.46
+++ Ns ++ Ns
LLF basophil 3.60±0.62 4.73±0.50 2.80±0.78 4.27±0.59 2.47±0.53 3.0±0.64 3.67±0.71
Ns Ns Ns Ns