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. 2014 Dec 13;33(2):490–495. doi: 10.1007/s10637-014-0197-z

Table 3.

Adverse drug reactions

Adverse drug reactions Grade 3 Grade 4
N % N %
Hematological
 Decreased neutrophil count 16 29.6 3 5.6
 Decreased lymphocyte count 9 16.7 0 0.0
 Decreased white blood cell count 5 9.3 0 0.0
 Decreased platelet count 4 7.4 1 1.9
 Anemia 2 3.7 0 0.0
Non-hematological
 Pneumocystis jiroveci pneumonia 1 1.9 0 0.0
 Thrombotic microangiopathy 1 1.9 0 0.0
 Decreased appetite 1 1.9 0 0.0
 Interstitial lung disease 1 1.9 0 0.0
  Elevated alanine aminotransferase level 1 1.9 0 0.0
  Elevated aspartate aminotransferase level 1 1.9 0 0.0
  Elevated blood glucose level 1 1.9 0 0.0
  Elevated gamma-glutamyltransferase level 1 1.9 0 0.0
  Elevated hepatic enzyme level 1 1.9 0 0.0