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Tumor weight (a) and tumor burden (b) of human pancreatic cancer Panc-1 mouse orthotopic model treated with PBI-05204, gemcitabine (Gemz) or a combination of PBI-05204 and gemcitabine for 6 weeks. PBI-05204 but not gemcitabine significantly inhibited the growth of Panc-1 tumors. Data are presented as Mean ± SD (n = 7 for the control and 8 for each treatment group). P < 0.05 is the level of statistical significance
