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. 2015 Jan 7;33(2):290–299. doi: 10.1007/s10637-014-0203-5

Table 1.

Effects of cytochalasin B against murine cancer lines in vitro

CB exposure time 3 h 2 days 3 days 4 days
IC concentrations (μM) IC50 IC80 IC50 IC80 IC50 IC80 IC50 IC80
M109c 2.56 12.23 0.83 6.02 0.42 3.77 0.25 0.75
B16F10 ND ND 0.80 3.50 0.46 1.59 0.37 1.21
B16BL6 10.46 44.86 2.10 20.04 0.96 17.03 0.87 10.41
P388/ADR 105.5 188.4 6.23 10.45 4.24 6.47 ND ND
P388/S 51.9 84.1a 3.10 5.02 ND ND ND ND

ND Not determined, a2.5 h