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. 2015 Apr 6;212(4):525–538. doi: 10.1084/jem.20141438

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© 2015 Tesio et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

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Figure 5. — CYLD–TRAF2 interaction has no significant effect on NF-κB signaling. (A) IκBα levels in BM HSCs from control and CYLDex7/8^−/− mice. (B) Expression analysis using qRT-PCR of NF-κB target genes in BM HSCs sorted from control and CYLDex7/8^−/− mice. (C) NIK expression analyzed by flow cytometry in BM HSCs from control and CYLDex7/8^−/− mice. Results are shown of two (A: 4/4; B: 5/7) or three (C: 4/6) independent experiments, with the numbers of analyzed control/mutant mice indicated in parentheses. Error bars indicate SEM. *, P < 0.05.