Table 3.
Comparisons of initial profiles in cases with and without malignant transformation of nodules
| Parameter | Malignant | Non-malignant | p value |
|---|---|---|---|
| Nodule, n | 19 | 73 | – |
| Nodule size (mm) | 12 (8–16) | 11 (8–20) | 0.8644a |
| US, hypo/hyper | 13/6 | 54/9 | 0.7727b |
| DN/LRN | 10/9 | 14/59 | 0.0066b |
| Age | 63 (24–73) | 67 (37–79) | 0.4719a |
| AST (IU/ml) | 60 (30–197) | 73 (15–400) | 0.1835a |
| ALT (IU/ml) | 58 (11–466) | 71 (11–466) | 0.1835a |
| Platelet (×104/μl) | 11.7 (7.2–20.9) | 11.2 (3.7–16.7) | 0.6477a |
| Child classification/NBNC | 12/4/3 | 54/11/8 | 0.9680c |
| AFP (ng/ml) | 12.5 (3.1–108.9) | 7.9 (1.8–657) | 0.5505a |
| PIVKA-II (mAU/ml) | 18 (<10–24) | 15 (<10–31) | 0.9382a |
| HCV/HBV/NBNC | 12/4/3 | 54/11/8 | 0.6469c |
| DM (+)/(−) | 3/16 | 8/65 | 0.6912b |
| Pre-HCC (+)/(−) | 1/18 | 10/64 | 0.2710b |
Data were shown as median and range
aMann–Whitney test
bFisher’s exact test
cChi-square test