Table 2. Correlation between familial cancer history and EGFR mutations in never smokers with NSCLC.

Characteristics	Negative EGFR mutation, n [%]	Positive EGFR mutation, n [%]	Total, n	OR (P value)	95% CI
Family history of any cancer				5.9 (<0.001)	3.3-10.6
Yes	28 [33]	57 [67]	85
No	120 [75]	41 [25]	161
Family history of lung cancer				7.5 (<0.001)	3.4-16.3
Yes	11 [28]	28 [72]	39
No	120 [75]	41 [25]	161
Family history of non-pulmonary cancer				5.0 (<0.001)	2.5-10.0
Yes	17 [37]	29 [63]	46
No	120 [75]	41 [25]	161

EGFR, epidermal growth factor receptor; NSCLC, non-small cell lung cancer; OR, odds ratio; CI, confidence interval; n, number of patients; No, no family history of cancer.