Table 3. Correlation between EGFR mutations and clinical characteristics in never smoking lung cancer patients with familial cancer history.
| Characteristics | Negative EGFR mutation, n [%] | Positive EGFR mutation, n [%] | Total, n | OR (P value) | 95% CI |
|---|---|---|---|---|---|
| Lung cancer stage | 2.1 (0.12) | 0.8-5.4 | |||
| Early (I-III) | 12 [44] | 15 [56] | 27 | ||
| Advanced (IV) | 16 [27] | 42 [73] | 58 | ||
| Gender | 4.9 (0.03) | 1.1-21.4 | |||
| Female | 22 [29] | 54 [71] | 76 | ||
| Male | 6 [67] | 3 [33] | 9 | ||
| Age, mean ± SD (years) | 58±10 | 60±11 | 60±10 | (0.51) |
P value, Pearson’s chi-squared test for categorical variables and t-test for continuous variables; EGFR, epidermal growth factor receptor; OR, odds ratio; CI, confidence interval; n, number of patients; SD, standard deviation.