Table 2. Contraindications for pediatric heart transplantation.
Absolute contraindications | Remarks |
Active infection | |
Ongoing malignancy | |
Medical noncompliance | |
Drug abuse | |
Non-reactive pulmonary vascular resistance | Left ventricular assist device implantation |
Presence of non-cardiac conditions that shortens life expectancy | |
Recent or unresolved pulmonary infarction | |
Psychiatric illness considered likely to interfere significantly with compliance | |
Systemic disease likely to limit post-transplant survival | |
Active peptic ulcer disease with recent gastrointestinal bleeding | Medical treatment and surveillance |
Relative contraindications | |
Renal insufficiency* | Combined heart and kidney transplant Ventricular assist device implantation |
History of malignancy | Depending on time after diagnosis |
Hepatic dysfunction* | Liver biopsy to exclude liver cirrhosis Combined heart and liver transplant |
Symptomatic peripheral or cerebrovascular disease. | |
Obesity (body mass index >32) |
*, not explained by the underlying heart failure and deemed irreversible.