Table 1. Diagnoses following EBUS-TBNA and final diagnoses.
| Final diagnosis (N=158) | EBUS-TBNA diagnosis | Number |
|---|---|---|
| Microbiologically confirmed tuberculosis (N=25) | Culture positive | 23 |
| Culture-negative, NAAT positive | 1 | |
| Necrotising granulomatous inflammationa | 1 | |
| Culture negative tuberculosisb (N=14) | Necrotising granulomatous inflammation | 3 |
| Non-necrotising granulomatous inflammation + clinical history | 9 | |
| Inadequate specimen | 2 | |
| Alternative diagnoses (N=119) | ||
| Sarcoidosis | Non-necrotising granulomatous | 78 |
| Reactive lymphadenopathy | Inflammation | 20 |
| NSCLC | Benign lymphoid material | 12 |
| NSCLC inadequate specimen | 1 | |
| Small cell lung cancer | Small cell lung cancer | 3 |
| Lymphoma | Lymphoma | 2 |
| Metastatic colon cancer | Metastatic colon cancer | 1 |
| Oesophageal cyst | Oesophageal cyst | 1 |
| Mycobacterium avium infection | Mycobacterium avium culture positive | 1 |
Necrotising granulomatous inflammation demonstrated on biopsy of alternative sites; a, endobronchial washings culture-positive for M. tuberculosis; b, see Table 2. EBUS-TBNA, endobronchial ultrasound transbronchial needle aspiration; NAAT, nucleic acid amplification techniques; NSCLC, non-small cell lung cancer.