Table 3. Summary of the most representative reports about HeartWare utilization in the setting of the BTT strategy.
| Author (Ref.), study period | Patients (n.) | Mean support time (days) | Competing outcomesa | Survival |
|---|---|---|---|---|
| Wieselthaler (24), 03/2006-11/2007 | 23 | 305 | HTx 21%, ongoing 60%, recovery 4%, death 13% | 6-month 91%, 12-month 86% |
| Strueber (20), 03/2006-12/2008 | 50 | 348 | HTx 40%, ongoing 34%, recovery 8%, death 18% | 6-month 90%, 12-month 84%, 24-month 79% |
| Aaronson (21), 08/2008-08/2010 | 140 | 249b | HTx 28%, ongoing 62%, recovery 0%, death 4% | 6-month 94%, 12-month 86% |
| Slaughter (22), 08/2008-12/2011 | 332 | 275b | HTx + recovery 21%, ongoing 67%, death 6% | 6-month 91%, 12-month 84% |
| Strueber (23), 02/2009-11/2012 | 254 | 363 | HTx 22%, ongoing 59%, recovery 1%, death 16% | 6-month 87%, 12-month 85%, 24-month 79% |
a, competing outcomes analysis must be reported to different follow-up periods (FUP): 12-month FUP (24), 12-month FUP (20), 6-month FUP (21), 6-month FUP (22); b, median support time; c, survival data are referred to as estimate of success (defined as survival to HTx, successful recovery with device explant or remaining on continued HeartWare support). BTT, bridge-to-transplantation; HTx, heart transplantation; NR, not reported.