Table 2. Diagnostic result of eligible studies.

Study	Year	TP	FP	FN	TN	Sensitivity/specificity (%)	AUC	Cut-off value	Reference standard	Detection of ACAR grade	Parameters	Field strength (T)
Wisenberg et al. (20)	1978	14	1	1	27	93.3/96.4	–	60 ms (2 SD)	EMB	≥2R	T2 relaxation time	0.15
Marie et al. (21)	1998	8	4	1	39	89/91	–	56 ms (2 SD)	EMB	≥2R	T2 relaxation time	0.5
Marie et al. (22)	2001	17	31	2	73	89/70	–	56 ms (2 SD)*	EMB	≥2R	T2 relaxation time	0.5
Taylor et al. (23)	2010	9	7	2	26	82/79&	0.84	3.5	EMB	≥2R	T1-early relative myocardial contrast enhancement	1.5
		6	3	5	30	55/90&	0.68	2	–	–	Relative elevated T2-STIR intensity
		11	9	0	24	100/73&	–	–	–	–	Combine the two parameters
Usman et al. (24)	2012	7	4	1	59	86.5/94.6#	–	56.4 ms	EMB or clinical presentation	≥2R	T2 relaxation time	1.5
		6	3	2	60	72/96#		60 ms*
Miller et al. (25)	2014	6	28	2	49	75/64	0.69	–	EMB	≥2R	Peak systolic circumferential strain	1.5
Krieghoff et al. (26)	2014	12	28	7	99	63/78$	0.724	2	EMB	≥1B	T2-STIR Edema ratio	1.5
		12	38	7	89	63/70$	–	4.5	–	–	T1-Global relative enhancement
		13	88	6	39	68/31$	0.659	–	–	–	–
		16	55	3	72	84/57$	–	–	–	–	Late gadolinium enhancement
		2	39	1	104	67/73$	–	–	–	≥2R	Combine the two parameters

*, pre-specified threshold value; ^&, corresponding to different CMR parameters; ^#, corresponding to different cut-off value; ^$, corresponding to different CMR parameters for different rejection grade. TP, true positive; FP, false positive; FN, false negative, TN, true negative; AUC, area under the curve; ACAR, acute cardiac allograft rejection; 2 SD, cut-off value more than 2 standard deviations above normal value; EMB, endomyocardial biopsy; STIR, short time inversion recovery; –, not mentioned.