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. 2015 Mar;7(3):400–406. doi: 10.3978/j.issn.2072-1439.2015.01.03

Figure 4.

Figure 4

Compound K failed to synergize cisplatin effects in H1299 cells. (A) H1299 cells were treated with indicated agents for 72 hr followed by MTT assay to determine cell viability; (B) or 24 hr followed by TUNEL staining for apoptosis analysis as in Figure 3B; (C) H460 cells were transfected with 40 nM control siRNA (si-SC) or p53 siRNA (si-p53) followed by treatment with 20 µM CK and 2.5 µM cisplatin either alone or in combination for 72 hr, and MTT assay was performed. Data are presented as mean ± SD. *, P<0.05 from untreated control; **, P<0.01 from single treatment.