Table 1. Demographics and co-morbidities stratified by BMI in patients with esophageal squamous carcinoma.
| Factors | Overweight (n=146) n (%) | Normal weight (n=753) n (%) | Underweight (n=277) n (%) | P value# |
|---|---|---|---|---|
| Sex | 0.41 | |||
| Male | 110 (75.3) | 598 (79.4) | 212 (76.5) | |
| Female | 36 (24.7) | 155 (20.6) | 65 (23.5) | |
| Age (years) (mean ± SD) | 57.1±9.8 | 57.8±9.4 | 58.1±10.1 | 0.60 |
| Anemia | 0.001 | |||
| Yes | 16 (11.0) | 136 (18.1) | 71 (25.6) | |
| No | 130 (89.0) | 617 (81.9) | 206 (74.4) | |
| Location of tumor | 0.04 | |||
| Upper thoracic | 10 (6.8) | 104 (13.8) | 34 (14.4) | |
| Mid-thoracic | 110 (75.3) | 469 (62.3) | 181 (65.3) | |
| Lower thoracic | 26 (17.9) | 180 (23.9) | 62 (20.3) | |
| Histology | <0.001 | |||
| Well | 31 (21.2) | 225 (29.9) | 121 (43.7) | |
| Moderately | 56 (38.4) | 255 (33.9) | 77 (27.8) | |
| Poorly and undifferentiated | 59 (40.4) | 273 (36.3) | 79 (28.5) | |
| The 6th T stage (AJCC) | 0.021 | |||
| T1 | 15 (11.7) | 46 (7.0) | 20 (8.4) | |
| T2 | 33 (25.8) | 139 (21.1) | 34 (14.2) | |
| T3 | 72 (56.3) | 409 (62.2) | 153 (64.0) | |
| T4 | 8 (6.2) | 64 (9.7) | 32 (13.4) | |
| The 6th N stage (AJCC) | 0.56 | |||
| N0 | 60 (46.9) | 277 (42.1) | 106 (44.4) | |
| N1 | 68 (63.1) | 381 (57.9) | 133 (55.6) | |
| The 6th M stage (AJCC) | 0.88 | |||
| M0 | 128 (87.6) | 658 (87.3) | 239 (86.3) | |
| M1 | 18 (12.4) | 95 (12.7) | 38 (13.7) | |
| The 6th TNM stage (AJCC) | 0.003 | |||
| I | 12 (8.2) | 37 (4.9) | 23 (8.3) | |
| IIA | 51 (34.9) | 248 (32.9) | 82 (29.6) | |
| IIB | 19 (13.0) | 77 (10.2) | 10 (3.6) | |
| III | 46 (31.5) | 296 (39.3) | 124 (44.8) | |
| IV | 18 (12.4) | 95 (12.7) | 38 (13.7) | |
| Number of lymph nodes collected in specimen | 10.1±3.4 | 10.4±3.9 | 9.9±3.4 | 0.28 |
| Status of resection margins | <0.001 | |||
| R0 | 123 (96.1) | 628 (95.4) | 222 (92.9) | |
| R1 | 5 (3.9) | 30 (4.6) | 17 (7.1) | |
| High blood pressure | <0.001 | |||
| Yes | 59 (40.4) | 150 (19.9) | 17 (6.1) | |
| No | 87 (59.6) | 603 (80.1) | 260 (93.9) | |
| Diabetes | <0.001 | |||
| Yes | 37 (25.3) | 100 (13.3) | 32 (11.6) | |
| No | 109 (74.7) | 653 (86.7) | 245 (88.4) | |
| Coronary artery diseases | <0.001 | |||
| Yes | 21 (14.5) | 75 (10.0) | 8 (2.9) | |
| No | 125 (85.5) | 678 (90.0) | 269 (97.1) | |
| Cerebrovascular diseases | 0.17 | |||
| Yes | 10 (6.8) | 36 (4.8) | 8 (2.9) | |
| No | 136 (93.2) | 717 (95.2) | 269 (97.1) | |
| COPD | 0.23 | |||
| Yes | 13 (8.8) | 50 (6.6) | 13 (4.7) | |
| No | 133 (91.2) | 703 (93.4) | 264 (95.3) | |
| Hernia | 0.44 | |||
| Yes | 4 (2.7) | 17 (2.3) | 7 (2.5) | |
| No | 142 (97.3) | 736 (97.7) | 270 (97.5) | |
| Smoking history | 0.93 | |||
| Yes | 88 (60.1) | 466 (61.9) | 170 (61.4) | |
| No | 58 (39.9) | 287 (38.1) | 107 (38.6) | |
| Adjuvant chemotherapy | 0.01 | |||
| Yes | 30 (20.5) | 93 (12.4) | 29 (10.5) | |
| No | 116 (79.5) | 660 (87.6) | 248 (89.5) | |
| Body weight | 0.035 | |||
| Weight loss | 57 (39.0) | 346 (45.9) | 144 (52.0) | |
| Weight stable | 89 (61.0) | 407 (54.1) | 133 (48.0) |
Overweight, BMI 25-29.9 kg/m2; normal, BMI 18.5-24.9 kg/m2; underweight, BMI <18.5 kg/m2. BMI, body mass index; AJCC, American Joint Committee on Cancer; TNM, Tumor-Node-Metastasis; COPD, chronic obstructive pulmonary disease. P value#, the comparison of demographics and comorbidities among three different BMI status.