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. 2015 Mar 25;13:24. doi: 10.1186/s12951-015-0080-x

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© Gong et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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MR images of HUVECs labeled with different concentrations of 30 and 50 nm GMNPs. With increasing concentrations, the signal intensity of the HUVECs labeled with the 30 and 50 nm GMNPs decreased rapidly. Consistent with the trend of the signal intensity, the T₂ relaxation time of the labeled cells decreased with increasing GMNP concentration.