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. 2015 Mar 18;13:13. doi: 10.1186/s12953-015-0069-2

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© Reichenbach et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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D1/D5 dopamine receptor-selective drugs differentially modulate frequency-modulated tone discrimination learning of 6JOla and 6J mice. Mice were trained in daily sessions to discriminate between rising and falling frequency-modulated tones. After session 1, they received intraperitoneal injections of vehicle (A), SCH23390 (B), SKF38393 (C), SKF83822 (D), SKF83959 (E), or a combination of SKF83822 and SKF83959 (F). Arrows indicate the approximate injection time. Discrimination rates D are presented as means ± S.E.M. n refers to the number of mice. ANOVA values are described in the text. *P < 0.05, significantly different from the corresponding value of the 6J subpopulation (unpaired t-test).