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. 2015 Apr 7;9:42. doi: 10.3389/fnana.2015.00042

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Copyright © 2015 Fua and Knott.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Light and electron microscopy neuronal trees. (A) Graph structure extracted from the electron microscopy image stack, in red. (B) Segmented light microscope neurons in blue. (C) After the non-linear registration process using ATS-RGM, the EM segmented neuron is deformed and aligned over the LM extracted neuron. (D) Registration using CPD, in yellow, which falls into a local minimum. (E) A zoom over the region where the EM stack has been extracted. The two neurons have been completely aligned. Best viewed in color.