Table 2.

Medication Use by Graft Vintage

Medication	Overall		Graft Vintage (y)						p-value**
			0.5 – <2		2 – 6		> 6
	N	%	N	%*	N	%*	N	%*
Immunosuppressive	4085	100	1194	100	1486	100	1405	100	ns
Cyclosporine A	2081	51	405	34	718	48	958	68	<0.001
Tacrolimus	1551	38	703	59	632	43	216	15	<0.001
Sirolimus	342	8	151	13	136	9	55	4	<0.001
Mycophenolate Mofetil	2672	65	919	77	1119	75	634	45	<0.001
Azathioprine	733	18	102	9	162	11	469	33	<0.001
Prednisone	3720	91	1080	90	1346	91	1294	92	ns
Blood Pressure Lowering	3620	89	1041	87	1326	89	1253	89	ns
ACE Inhibitors	1336	33	291	24	521	35	524	37	<0.001
Angiotensin Receptor Blockers	545	13	114	10	196	13	235	17	<0.001
Beta Blockers	2306	56	739	62	851	57	716	51	<0.001
DHP-CCB	1430	35	419	35	502	34	509	36	ns
NDHP-CCB	242	6	60	5	80	5	102	7	0.014
Loop Diuretics	1222	30	351	29	418	28	453	32	0.095
Other Diuretics	401	10	85	7	161	11	155	11	0.001
Lipid Lowering	2264	55	577	48	857	58	830	59	<0.001
HMG COA Reductase Inhibitors	2146	53	539	45	816	55	791	56	<0.001
Other Lipid Lowering	290	7	71	6	110	7	109	8	0.078
Anti-Platelet Agents	1744	43	564	47	623	42	557	40	<0.001
Aspirin	1685	41	541	45	607	41	537	38	<0.001
Clopidogrel	99	2	36	3	28	2	35	2	ns
Other Anti-platelet	34	1	7	1	9	1	18	1	0.045
Anti-Coagulants	197	5	58	5	66	4	73	5	ns
Warfarin	193	5	57	5	65	4	71	5	ns
Heparin	6	0	1	0	1	0	4	0	ns
Anti-Diabetic Agents	1196	29	391	33	443	30	362	26	<0.001
Insulin	904	22	310	26	326	22	268	19	<0.001
Sulfonylureas	312	8	87	7	117	8	108	8	ns
Rosigliatazone	74	2	22	2	36	2	16	1	ns
Pioglitazone	62	2	18	2	27	2	17	1	ns
Metformin	68	2	21	2	24	2	23	2	ns
Other Anti-Diabetic Agents	30	1	5	0	17	1	8	1	ns

Abbreviations: ACE Inhibitors: angiotensin-converting enzyme inhibitors; DHP-CCB: Dihydropyridine Calcium Channel Blockers; NDHP-CCB: Non-Dihydropyridine Calcium Channel Blockers.

Note: Data for 21 participants with missing graft vintage are omitted from this table.

^*Denominator is number of participants in the vintage category.

^**P-value is from the Cochran-Armitage test for trend; ns: p >0.10.