Table 4.

Outcome of patients with acute respiratory distress syndrome according to transpulmonary bubble transit

	Transpulmonary bubble transit
	Absent-or-minor ( n  = 159)	Moderate-to-large ( n  = 57)	p value
Pneumothorax, n (%)	8 (5%)	2 (4%)	0.64
Adjunctive therapy, n (%)
Prone positioning	50 (31%)	12 (21%)	0.14
Nitric oxide	37 (23%)	14 (25%)	0.84
ICU mortality, n (%)	73 (46%)	34 (60%)	0.08
Hospital mortality, n (%)	76 (48%)	36 (63%)	0.046
28-day ventilator-free days, mean ± SD	9 ± 10	4 ± 8	<0.01
28-day ICU-free days, mean ± SD	6 ± 9	3 ± 6	<0.01
ICU survivors (n = 109)	(n = 86)	(n = 23)
MV duration, mean days ± SD	16 ± 28	28 ± 30	<0.01
ICU duration, mean days ± SD	25 ± 35	35 ± 33	0.03

ICU, intensive care unit; MV, mechanical ventilation; SD, standard deviation.