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. 2015 Apr 1;10:2619–2634. doi: 10.2147/IJN.S80025

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© 2015 Cai et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Representative images of immunohistochemical staining of MDA-MB-231 tumor tissues by incubating with M-HFn nanoparticles (DAB as the substrate).

Notes: (A) Without M-HFn nanoparticle incubation. Incubated with (B) M-HFn₁₀₀₀, (C) M-HFn₃₀₀₀, (D) M-HFn₅₀₀₀, and (E) M-HFn₇₀₀₀. (F) Different density mean shows that the tissue sections treated with M-HFn nanoparticles of larger core sizes enhance the efficiency of immunohistochemical staining (P<0.05).

Abbreviations: M-HFn, ferrimagnetic H-ferritin; DAB, 3,3′-diaminobenzidine tetrahydrochloride.