. Author manuscript; available in PMC: 2015 Apr 7.

Published in final edited form as: Biochim Biophys Acta. 2014 Nov 18;1853(2):276–284. doi: 10.1016/j.bbamcr.2014.11.015

Table 1.

Metabolic, biochemical, bioenergetic and morphological differences between rat H9c2 ventricle and mouse HL-1 atrial cells with cardiac phenotype.

Parameter/criteria	H9c2 cardiomyoblasts	HL-1 cells
Citrate synthase (CS)^a Mitochondrial marker	↑	↓
ATP content^a Cellular energy status	↑	↓
Cellular/mitochondrial State 3 maximal respiration	↑	↓
Uncoupled respiration	↑	↓
Uncoupled control ratio (UCR)	↑	↓
Mitochondrial morphology Discrete mitochondria	↑	↓
Mitochondrial morphology Mitochondrial network	↓	↑
Tubulin beta-II (mitochondrial isotype)	+	--
Sensitivity to hypoxia-reoxygenation	↑	↓
Phospho-AMP activated protein kinase (pAMPK)	↑	↓
PGC-1α	↓	↑

Calculated per 10⁶ cells.