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The primary, secondary and tertiary structure of TesB with α-helices coloured red, β-strands yellow and loops green. (a) The double hotdog-domain structure of YpTesB. (b) The two hotdog domains of YpTesB, with a superposition of the domains (r.m.s.d. of 0.33 Å) and sequence alignment, and (c) a comparison of three TesB structures from Y. pestis (PDB entry 4qfw), E. coli (PDB entry 1c8u) and M. marinum (PDB entry 3u0a), revealing a conserved β-bulge through the HD2 α-helix.
