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. 2015 Apr 7;10(4):e0125338. doi: 10.1371/journal.pone.0125338

Table 1. Characteristics of the participants according to the presence or absence of chronic kidney disease in a diabetic population.

CKD P eGFR< 60 P Proteinuria P
absence presence absence presence absence presence
Sex (%) 0.408 0.833 0.008
male 54.2(1.8) 58.2(4.2) 54.7(1.7) 53.6(5.1) 55.0(1.7) 72.8(5.7)
female 45.8(1.8) 41.8(4.2) 45.3(1.7) 46.4(5.1) 45.0(1.7) 27.2(5.7)
Age (years) <.001
19–29 1.3(0.6) 1.3(1.3)
30–39 6.4(0.9) 4.4(2.0)
40–49 20.4(1.7) 5.8(2.9)
50–59 28.0(1.6) 19.3(3.4)
60–69 26.3(1.4) 28.2(3.9)
≥70 17.6(1.3) 41.0(4.5)
Education (> 6 yrs) 60.6(1.9) 49.9(4.5) 0.022 60.8(1.8) 42.6(5.1) <.001 58.9(1.8) 69.4(6.0) 0.110
Ever-smoker (yes) 48.6(1.7) 48.9(4.3) 0.945 48.5(1.7) 50.4(4.7) 0.693 49.0(1.7) 53.4(7.5) 0.572
Heavy drinker (yes) 20.9(1.9) 15.8(4.4) 0.316 20.7(1.9) 16.0(5.5) 0.444 20.7(1.9) 19.6(7.5) 0.889
Regular exercise (yes) 26.2(1.6) 13.9(2.7) <.001 25.9(1.6) 12.5(3.0) 0.001 25.6(1.5) 13.1(3.8) 0.012
MI (> = 25 kg/m2) 49.8(1.8) 52.8(4.6) 0.014 50.3(1.7) 47.8(4.9) 0.181 49.2(1.8) 60.3(7.3) 0.121
MetS components
High WC 56.3(1.8) 57.1(4.4) 0.860 56.1(1.8) 59.8(4.8) 0.472 56.0(1.8) 53.7(7.3) 0.766
Low HDL 62.3(1.7) 74.9(4.2) 0.009 62.3(1.7) 80.1(4.1) <.001 62.6(1.7) 72.2(7.0) 0.203
High glucose 89.1(1.0) 83.6(3.0) 0.058 89.3(1.0) 77.8(4.0) <.001 88.4(1.0) 90.3(4.0) 0.678
High triglycerides 55.5(1.7) 60.0(4.4) 0.347 55.5(1.7) 61.7(4.7) 0.224 55.4(1.7) 60.0(7.5) 0.563
High blood pressure 61.5(1.9) 82.3(3.3) <.001 62.2(1.8) 83.0(3.8) <.001 62.8(1.7) 84.5(4.6) <.001
Systolic blood pressure (mmHg) 124.4(0.6) 128.9(1.6) 0.009 124.6(0.6) 128.5(1.9) 0.053 124.5(0.6) 131.6(2.2) 0.002
Diastolic blood pressure (mmHg) 77.1(0.4) 75.3(1.0) 0.104 77.2(0.4) 72.9(1.1) <.001 76.9(0.3) 79.6(1.4) 0.051
DM duration (> = 5 yr) 57.5(2.2) 80.6(4.2) <.001 58.0(2.1) 84.0(4.1) <.001 59.4(2.1) 79.3(7.4) 0.031
DM control (yes) 29.2(1.8) 32.7(4.3) 0.445 29.1(1.7) 35.6(4.7) 0.188 29.4(1.7) 25.0(7.0) 0.333
HbA1c 7.3(0.1) 7.4(0.1) 0.582 7.3(0.1) 7.3(0.2) 0.753 7.3(0.1) 7.7(0.2) 0.162
DMR <.001 0.025 <.001
NPDR 15.6(1.8) 29.6(6.1) 16.4(1.8) 24.9(6.6) 16.3(1.8) 37.5(10.3)
PDR 1.8(0.5) 5.5(2.8) 1.8(0.5) 7.1(4.0) 1.8(0.5) 4.9(3.7)
CSME 1.4(0.5) 6.4(2.7) 1.7(0.5) 4.1(3.0) 1.4(0.5) 12.8(6.0)

Data are presented as the mean±SE or % (SE). Abbreviation: CKD, chronic kidney disease; DM, diabetes mellitus; BMI, body mass index; MetS, metabolic syndrome; WC, waist circumference; HDL, high density lipoprotein; NPDR, non-proliferative diabetic retinopathy; PDR, proliferative diabetic retinopathy; CSME, clinically significant macular edema. DM control means HbA1c<6.5.