Fig 6. MAb binding to HIV-1BG505 Env variants on the cell surface.
The binding of PGT121 (A) and PG9 (B and C) to HIV-1BG505 Env ΔCT variants expressed on the cell surface was measured by cell-based ELISA. The data in (C) were generated in the presence of 80 nM sCD4. The means and SEM derived from at least three independent experiments performed in quadruplicate are shown. Statistical significance was assessed using a paired t-test, and is indicated as described in the legend to Fig 1 of the main text.