Fig 9. Ligand binding to HIV-1BG505 full-length wild-type and I559P Env variants.
The binding of wild-type (wt) and I559P HIV-1BG505 Env full-length (gp160) variants expressed on the cell surface was measured by cell-based ELISA, and is plotted relative to the binding of the 2G12 antibody. The ligands are arranged according to the relative binding to wt Env. The means and SEM derived from four independent experiments performed in quadruplicate are shown. Statistical significance was assessed using a paired t-test, and the degree of significance is indicated: ***—p < 0.001, **—p < 0.01, *—p < 0.05 and ns—not significant.