Figure 2.

Lactobacillus acidophilus NCK2187 promotes intestinal regulation in steady state

• A B6 mice were orally gavaged with 10⁹ CFU NCK56 (blue) or NCK2187 (green) on days 0, 3, 6, and 9, or left untreated, and immune responses in the colon analyzed at day 14 by flow cytometry.
• B, C B6 FoxP3-GFP mice were treated and evaluated as in (A). Regulatory cytokine production in FoxP3-GFP⁺ (green-dotted bars) versus FoxP3-GFP⁻ (white bars) cells was measured by intracellular staining and FACS analyses (C).

Data information: For all data shown, n = 5 mice/group. Data represent four individual experiments and are shown as mean ± SEM. *P < 0.05, **P < 0.01, ****P < 0.0001. Black asterisks compare NCK2187 to untreated (PBS) mice, and red asterisks to NCK56-treated mice.