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. 2015 Apr 7;10(4):e0122286. doi: 10.1371/journal.pone.0122286

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© 2015 Malyshev et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 2 — A: Membrane potential responses (blue traces) of a layer 2/3 pyramidal neuron expressing ChR2 to a 488 nm diode light modulated by sine-wave signals at 10, 50 and 100 Hz (light blue traces). The amplitude of the sine-wave modulation of light intensity was kept constant. B: Membrane potential responses (red traces) of a neuron to injection of sine-wave current at 10, 50 and 100 Hz (green traces). Two-electrode experiment. One electrode was used for current injection, and another electrode for recording of membrane potential responses. The amplitude of the sine-wave current was kept constant. C: Attenuation of the amplitude of membrane potential modulation in responses to sine-wave signals of different frequencies injected through the intracellular electrode or induced by photostimulation.