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. 2015 Apr 7;10(4):e0122519. doi: 10.1371/journal.pone.0122519

Fig 7. eIF4G2 function in the spermatocytes is essential for meiotic divisions during spermatogenesis.

Fig 7

Co-staining of wild-type testes (A-A'', C-C'') and testes expressing shRNA targeting eIF4G2 using bam-Gal4:VP16 driver (B-B'', D-D'') with anti-eIF4G2 (green) and anti-eIF4E-3 (red) antibody. Knockdown of eIF4G2 in the spermatocytes does not affect eIF4E-3 distribution at the apical tip of the testes (compare A' with B') but causes meiotic arrest and results in degenerating germ cells at the distal end (D-D''). The merged images are shown in A''-D''. DNA is stained with DAPI (magenta). Scale bar 100 μm.