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. 2015 Apr 7;10(4):e0120786. doi: 10.1371/journal.pone.0120786

Table 1. Results of ABVN-SEP, AEP and TrigN-SEP.

main effect PD CTRL
ABVN-SEP latency [ms] group F(3,180) = 2.544 p = 0.058 P1 2.7 ± 0.5 2.8 ± 0.6
side F(3,180) = 0.792 p = 0.500 N1 4.5 ± 0.9 4.6 ± 1.0
group * side F(3,180) = 0.692 p = 0.558 P2 6.3 ± 1.2 6.1 ± 1.2
MoCA F(3,180) = 1.804 p = 0.148
amplitude[μV] group F(2,140) = 0.180 p = 0.835 P1-N1 11.8 ± 12.4 12.1 ± 11.3
side F(2,140) = 0.516 p = 0.598 N1-P2 6.8 ± 11.1 6.3 ± 6.4
group * side F(2,140) = 0.568 p = 0.568
MoCA F(2,140) = 0.491 p = 0.613
AEP latency [ms] group F(5,189) = 0.310 p = 0.906 I 1.8 ± 0.2 1.8 ± 0.2
side F(5,189) = 0.316 p = 0.903 II 3.0 ± 0.2 3.0 ± 0.1
group * side F(5,189) = 0.445 p = 0.817 III 4.0 ± 0.2 4.0 ± 0.2
IV 5.3 ± 0.2 5.2 ± 0.2
V 5.9 ± 0.2 5.9 ± 0.2
TrigN-SEP latency [ms] group F(3,193) = 0.659 p = 0.578 N13 13.9 ± 1.2 13.9 ± 1.0
side F(3,193) = 0.564 p = 0.639 P19 20.6 ± 1.6 20.4 ± 1.2
group * side F(3,193) = 1.882 p = 0.134 N27 28.1 ± 2.5 27.7 ± 1.5

Results of ABVN-SEP (recording site O1-T3/O2-T4), AEP (A1/2-Cz) and TrigN-SEP (C5/C6-Fz; mean ± SD). The main effect of the MAN(C)OVA for peak latencies and amplitudes is indicated. There were no group differences between groups in the other recordings-sites either after correction for multiple comparisons (ABVN-SEP). PD, patients with Parkinson’s disease; CTRL, healthy control subjects; ABVN-SEP, somatosensory evoked potentials following electric stimulation of the auricular branch of the vagus nerve; AEP, auditory evoked potentials; TrigN-SEP, somatosensory evoked potentials following electric stimulation of the trigeminal nerve.