Table 1. Results of ABVN-SEP, AEP and TrigN-SEP.
main effect | PD | CTRL | |||||
---|---|---|---|---|---|---|---|
ABVN-SEP | latency [ms] | group | F(3,180) = 2.544 | p = 0.058 | P1 | 2.7 ± 0.5 | 2.8 ± 0.6 |
side | F(3,180) = 0.792 | p = 0.500 | N1 | 4.5 ± 0.9 | 4.6 ± 1.0 | ||
group * side | F(3,180) = 0.692 | p = 0.558 | P2 | 6.3 ± 1.2 | 6.1 ± 1.2 | ||
MoCA | F(3,180) = 1.804 | p = 0.148 | |||||
amplitude[μV] | group | F(2,140) = 0.180 | p = 0.835 | P1-N1 | 11.8 ± 12.4 | 12.1 ± 11.3 | |
side | F(2,140) = 0.516 | p = 0.598 | N1-P2 | 6.8 ± 11.1 | 6.3 ± 6.4 | ||
group * side | F(2,140) = 0.568 | p = 0.568 | |||||
MoCA | F(2,140) = 0.491 | p = 0.613 | |||||
AEP | latency [ms] | group | F(5,189) = 0.310 | p = 0.906 | I | 1.8 ± 0.2 | 1.8 ± 0.2 |
side | F(5,189) = 0.316 | p = 0.903 | II | 3.0 ± 0.2 | 3.0 ± 0.1 | ||
group * side | F(5,189) = 0.445 | p = 0.817 | III | 4.0 ± 0.2 | 4.0 ± 0.2 | ||
IV | 5.3 ± 0.2 | 5.2 ± 0.2 | |||||
V | 5.9 ± 0.2 | 5.9 ± 0.2 | |||||
TrigN-SEP | latency [ms] | group | F(3,193) = 0.659 | p = 0.578 | N13 | 13.9 ± 1.2 | 13.9 ± 1.0 |
side | F(3,193) = 0.564 | p = 0.639 | P19 | 20.6 ± 1.6 | 20.4 ± 1.2 | ||
group * side | F(3,193) = 1.882 | p = 0.134 | N27 | 28.1 ± 2.5 | 27.7 ± 1.5 |
Results of ABVN-SEP (recording site O1-T3/O2-T4), AEP (A1/2-Cz) and TrigN-SEP (C5/C6-Fz; mean ± SD). The main effect of the MAN(C)OVA for peak latencies and amplitudes is indicated. There were no group differences between groups in the other recordings-sites either after correction for multiple comparisons (ABVN-SEP). PD, patients with Parkinson’s disease; CTRL, healthy control subjects; ABVN-SEP, somatosensory evoked potentials following electric stimulation of the auricular branch of the vagus nerve; AEP, auditory evoked potentials; TrigN-SEP, somatosensory evoked potentials following electric stimulation of the trigeminal nerve.